MULTIOMICS ANALYSIS OF HUMAN SERUM AND ANIMAL EXPERIMENTS REVEALS THE PROTECTIVE MECHANISM OF QINGRE HUOXUE DECOCTION AGAINST RHEUMATOID ARTHRITIS

Multiomics analysis of human serum and animal experiments reveals the protective mechanism of Qingre Huoxue Decoction against rheumatoid arthritis

ObjectiveQingre Huoxue Decoction (QRHXD) is a traditional Chinese herbal prescription widely used in clinical practice with significant therapeutic effects on RA; however, its mechanism of action remains unclear.This study aimed to investigate the efficacy and underlying mechanisms of QRHXD in treating RA through clinical research, multiomics appro

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Kalirin-7 plays the neuroprotective role in Neuro-2A cells injured by oxygen-glucose deprivation and reperfusion through Rac1 activation

Objective(s): The study explored the neuroprotective role of Kalirin-7 (Kal-7) in Neuro-2A cells after oxygen-glucose deprivation and reperfusion (OGD/R) treatment.Materials and Methods: The study used an OGD/R model of mouse Neuro-2A neuroblastoma cells in vitro.Cells were transfected with pCAGGS-Kal-7 to up-regulating kal-7.Then Proteolytic Enzym

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Characterization of the Water Shortage Effects on Potato Tuber Tissues during Growth Using MRI Relaxometry and Biochemical Parameters

The potato Phone Double Adaptor is one of the most cultivated crops worldwide, providing an important source of food.The quality of potato tubers relates to their size and dry matter composition and to the absence of physiological defects.It depends on the spatial and temporal coordination of growth and metabolic processes in the major tuber tissue

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